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Article

Association between HLA alleles and Epstein-Barr virus Zta-IgA serological status in healthy males from southern China.

The journal of gene medicine - 1 Nov 2021

Yuan Lei-Lei, Deng Chang-Mi, Xue Wen-Qiong, He Yong-Qiao, Wang Tong-Min, Zhang Jiang-Bo, Yang Da-Wei, Zhou Ting, Wu Zi-Yi, Liao Ying, Zheng Mei-Qi, Li Dan-Hua, Cao Lian-Jing, Jia Yi-Jing, Zhang Wen-Li, Xiao Ruo-Wen, Luo Lu-Ting, Tong Xia-Ting, Wu Yan-Xia, Huang Jing-Wen, Jia Wei-Hua

Abstract excerpt

BACKGROUND: Nasopharyngeal carcinoma (NPC), an Epstein-Barr virus (EBV) associated cancer, exhibits an extremely high incidence in southern Chinese. Given that human leukocyte antigen (HLA) plays critical roles in antigen presentation and relates to NPC susceptibility, it is speculated that certain HLA variants may affect EBV reactivation, which is a key pathogenic factor of NPC. Therefore, we attempted to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34164868
DOI: 10.1002/jgm.3375
PMCID: PMC8596395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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