Article
Association of HLA class I and II alleles and extended haplotypes with nasopharyngeal carcinoma in Taiwan.
Journal of the National Cancer Institute - 4 Dec 2002
Hildesheim Allan, Apple Raymond J, Chen Chien-Jen, Wang Sophia S, Cheng Yu-Juen, Klitz William, Mack Steven J, Chen I-How, Hsu Mow-Ming, Yang Czau-Siung, Brinton Louise A, Levine Paul H, Erlich Henry A
Abstract excerpt
BACKGROUND: Nasopharyngeal carcinoma (NPC), which occurs at a disproportionately high rate among Chinese individuals, is associated with Epstein-Barr virus (EBV). Human leukocyte antigen (HLA) polymorphisms appear to play a role in NPC, because they are essential in the immune response to viruses...
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