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Elevated TYROBP expression predicts poor prognosis and high tumor immune infiltration in patients with low-grade glioma

23 Jun 2021

Abstract excerpt

BACKGROUND: Tyrosine protein tyrosine kinase binding protein (TYROBP) binds non-covalently to activated receptors on the surface of various immune cells, and mediates signal transduction and cellular activation. It is dysregulated in various malignancies, although little is known regarding its role in low-grade glioma. The aim of this study is to explore the clinicopathological significance, prognostic value and...

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PMID: 34162355
DOI: 10.1186/s12885-021-08456-6

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