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Article

Genome-wide association study of signature genetic alterations among pseudomonas aeruginosa cystic fibrosis isolates.

PLoS pathogens - 1 Jun 2021

Hwang Wontae, Yong Ji Hyun, Min Kyung Bae, Lee Kang-Mu, Pascoe Ben, Sheppard Samuel K, Yoon Sang Sun

Abstract excerpt

Pseudomonas aeruginosa (PA) is an opportunistic pathogen that causes diverse human infections including chronic airway infection in patients with cystic fibrosis (CF). Comparing the genomes of CF and non-CF PA isolates has great potential to identify the genetic basis of pathogenicity. To gain a deeper understanding of PA adaptation in CF airways, we performed a genome-wide association study (GWAS) on 1,001 PA...

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Identifiers

PMID: 34161396
DOI: 10.1371/journal.ppat.1009681
PMCID: PMC8274868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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