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Article

A proteomic investigation of isogenic radiation resistant prostate cancer cell lines

21 Jun 2021

Abstract excerpt

To model the problem of radiation resistance in prostate cancer, cell lines mimicking a clinical course of conventionally fractionated or hypofractionated radiotherapy have been generated. Proteomic analysis of radiation resistant and radiosensitive DU145 prostate cancer cells detected 4410 proteins. Over 400 proteins were differentially expressed across both radiation resistant cell lines and pathway analysis...

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PMID: 34152685
DOI: 10.1002/prca.202100037

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