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Mitochondrial perturbation reduces susceptibility to xenobiotics through altered efflux in Candida albicans

18 Jun 2021

Abstract excerpt

Candida albicans is a leading human fungal pathogen, which can cause superficial infections or life-threatening systemic disease in immunocompromised individuals. The ability to transition between yeast and filamentous forms is a major virulence trait of C. albicans, and a key regulator of this morphogenetic transition is the molecular chaperone Hsp90. To explore the mechanisms governing C. albicans morphogenesis...

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PMID: 34143207
DOI: 10.1093/genetics/iyab095

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