Article
A 1p/19q Codeletion-Associated Immune Signature for Predicting Lower Grade Glioma Prognosis.
Cellular and molecular neurobiology - 1 Apr 2022
Xu Jie, Liu Fang, Li Yuntao, Shen Liang
Abstract excerpt
Lower grade gliomas (LGGs) with codeletion of chromosomal arms 1p and 19q (1p/19 codeletion) have a favorable outcome. However, its overall survival (OS) varies. Here, we established an immune signature associated with 1p/19q codeletion for accurate prediction of prognosis of LGGs. The Chinese Glioma Genome Atlas (CGGA) and The Cancer Genome Atlas (TCGA) databases with RNA sequencing and corresponding clinical...
Topics
- Brain Neoplasms
- Glioma
- Humans
- Isocitrate Dehydrogenase
- Mutation
- Survival Rate
