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Article

An Axin2 mutation and perinatal risk factors contribute to sagittal craniosynostosis: evidence from a Chinese female monochorionic diamniotic twin family.

Hereditas - 16 Jun 2021

Xu Jin, Yan Qing, Song Chengcheng, Liang Jingjia, Zhao Liang, Zhang Xin, Weng Zhenkun, Xu Cheng, Liu Qian, Xu Shuqin, Pang Lu, Zhang Liye, Sun Yuan, Wang Gang, Gu Aihua

Abstract excerpt

BACKGROUND: Craniosynostosis, defined as premature fusion of one or more cranial sutures, affects approximately 1 in every 2000-2500 live births. Sagittal craniosynostosis (CS), the most prevalent form of isolated craniosynostosis, is caused by interplay between genetic and perinatal environmental insults. However, the underlying details remain largely unknown. METHODS: The proband (a female monochorionic twin...

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Identifiers

PMID: 34134783
DOI: 10.1186/s41065-021-00182-0
PMCID: PMC8210395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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