Article
The association of polymorphisms in related circadian rhythm genes and clopidogrel resistance susceptibility.
Basic & clinical pharmacology & toxicology - 1 Sept 2021
Su Jia, Yu Qinglin, Yang Jin, Zheng Nan, Zhong Jinyan, Ji Lindan, Li Jiyi, Chen Xiaomin
Abstract excerpt
Previous studies have confirmed that a dynamic change in circadian rhythm will affect platelet activity, resulting in clopidogrel resistance (CR). We attempted to evaluate whether polymorphisms of related circadian rhythm genes are involved in CR in stable coronary artery disease (SCAD) patients. A sum of 204 SCAD patients met our requirements and were recruited, and 96 patients were considered to have CR. After...
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