Article
[Germline and Somatic Mutations in Archived Breast Cancer Specimens of Different Subtypes].
Molekuliarnaia biologiia - 1 Jan 2000
Abramov I S, Korneva Yu S, Shisterova O A, Ikonnikova A Yu, Emelyanova M A, Lisitsa T S, Krasnov G S, Nasedkina T V
Abstract excerpt
Molecular profiling of tumors may provide promising options for personalized treatment. We have examined the spectrum of germline and somatic mutations in 23 breast cancers (ВС) of various molecular subtypes, including tumors 1) with expression of estrogen, progesterone and/or epidermal growth factor receptor HER2/neu, and 2) with a triple negative phenotype. Genomic DNA specimens were isolated from archived...
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