Article
Global Cardiovascular Risk Profile and Cerebrovascular Abnormalities in Presymptomatic Individuals with CADASIL or Autosomal Dominant Alzheimer's Disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2021
Schoemaker Dorothee, Velilla-Jimenez Lina, Zuluaga Yesica, Baena Ana, Ospina Carolina, Bocanegra Yamile, Alvarez Sergio, Ochoa-Escudero Martin, Guzmán-Vélez Edmarie, Martinez Jairo, Lopera Francisco, Arboleda-Velasquez Joseph F, Quiroz Yakeel T
Abstract excerpt
BACKGROUND: Cardiovascular risk factors increase the risk of developing dementia, including Alzheimer's disease and vascular dementia. OBJECTIVE: Studying individuals with autosomal dominant mutations leading to the early onset of dementia, this study examines the effect of the global cardiovascular risk profile on early cognitive and neuroimaging features of Alzheimer's disease and vascular dementia. METHODS: We...
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