Article
miR‐29c‐3p regulates TET2 expression and inhibits autophagy process in Parkinson's disease models
4 Jun 2021
Abstract excerpt
Abstract Autophagy in dopamine (DA) neurons is concerned to be associated with Parkinson's disease (PD), but the detailed mechanism remains unknown. Herein, we aimed to investigate the function of microRNA (miR)‐29c‐3p in autophagy in PD models. Intraperitoneal injection of MPTP (20 mg/kg) was given to C57BL/6 mice to establish PD mouse model. SH‐SY5Y cells were treated with MPP+ (1 mmol/L) to establish in vitro...
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