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Article

CXCL1 Regulated by miR-302e Is Involved in Cell Viability and Motility of Colorectal Cancer via Inhibiting JAK-STAT Signaling Pathway

17 May 2021

Abstract excerpt

Purpose This study made a systemic description for the CXCL1-dependent regulatory mechanism in colorectal cancer (CRC). Methods Bioinformatics methods were applied to obtain target mRNA CXCL1 and corresponding upstream miRNA. qRT-PCR and Western blot were performed to measure the levels of CXCL1 and miR-302e in CRC tissue and cells. Experiments including CCK-8, wound healing assay, Transwell invasion assay, and...

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PMID: 34079750
DOI: 10.3389/fonc.2020.577229

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