Mechnetor: a web server for exploring protein mechanism and the functional context of genetic variants.

doi:10.1093/nar/gkab399

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Article

Mechnetor: a web server for exploring protein mechanism and the functional context of genetic variants.

Nucleic acids research - 2 Jul 2021

González-Sánchez Juan Carlos, Ibrahim Mustafa F R, Leist Ivo C, Weise Kyle R, Russell Robert B

Abstract excerpt

Advances in DNA sequencing and proteomics mean that researchers must now regularly interrogate thousands of positional gene/protein changes in order to find those relevant for potential clinical application or biological insights. The abundance of already known information on protein interactions, mechanism, and tertiary structure provides the possible means to understand these changes rapidly, though a careful...

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PMID: 34076240
DOI: 10.1093/nar/gkab399
PMCID: PMC8262711

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