Article
Association of heart rate and diabetes among 0.5 million adults in the China Kadoorie biobank: Results from observational and Mendelian randomization analyses.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 22 Jul 2021
Wang Wenxiu, Wang Jingjia, Lv Jun, Yu Canqing, Shao Chunli, Tang Yida, Guo Yu, Bian Zheng, Du Huaidong, Yang Ling, Millwood Iona Y, Walters Robin G, Chen Yiping, Chang Liang, Fan Lei, Chen Junshi, Chen Zhengming, Huang Tao, Li Liming
Abstract excerpt
BACKGROUND AND AIMS: Observational studies have associated resting heart rate with incident diabetes. Whether the associations are causal remains unclear. We aimed to examine the shape and strength of the associations and assessed the causal relevance of such associations in Chinese adults. METHODS AND RESULTS: The China Kadoorie Biobank enrolled 512,891 adults in China. Cox proportional hazard regression models...
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