Article
Identification of A-to-I RNA editing profiles and their clinical relevance in lung adenocarcinoma.
Science China. Life sciences - 1 Jan 2022
Wang Cheng, Huang Mingtao, Chen Congcong, Li Yuancheng, Qin Na, Ma Zijian, Fan Jingyi, Gong Linnan, Zeng Hui, Yang Liu, Xu Xianfeng, Zhou Jun, Dai Juncheng, Jin Guangfu, Hu Zhibin, Ma Hongxia, Tan Fengwei, Shen Hongbing
Abstract excerpt
Adenosine-to-inosine (A-to-I) RNA editing is a widespread posttranscriptional modification that has been shown to play an important role in tumorigenesis. Here, we evaluated a total of 19,316 RNA editing sites in the tissues of 80 lung adenocarcinoma (LUAD) patients from our Nanjing Lung Cancer Cohort (NJLCC) and 486 LUAD patients from the TCGA database. The global RNA editing level was significantly increased in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.