Article
HLA-G expression correlates with histological grade but not with prognosis in colorectal carcinoma.
HLA - 1 Sept 2021
Kaprio Tuomas, Sariola Hannu, Linder Nina, Lundin Johan, Kere Juha, Haglund Caj, Wedenoja Satu
Abstract excerpt
Trophoblast-specific expression of HLA-G induces immune tolerance for the developing fetus. Pathological HLA-G expression later in life might contribute to immune escape of various cancers. We studied the still controversial role of HLA-G in colorectal carcinoma (CRC) using the MEM-G/1 antibody and a tissue microarray series of CRC tumors (n = 317). HLA-G expression appeared in 20% of the tumors and showed high...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
