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IL-30† (IL-27A): a familiar stranger in immunity, inflammation, and cancer

1 May 2021

Abstract excerpt

Over the years, interleukin (IL)-27 has received much attention because of its highly divergent, sometimes even opposing, functions in immunity. IL-30, the p28 subunit that forms IL-27 together with Ebi3 and is also known as IL-27p28 or IL-27A, has been considered a surrogate to represent IL-27. However, it was later discovered that IL-30 can form complexes with other protein subunits, potentially leading to...

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PMID: 34045653
DOI: 10.1038/s12276-021-00630-x

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