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Article

Development and Validation of a CD8+ T Cell Infiltration-Related Signature for Melanoma Patients.

Frontiers in immunology - 1 Jan 2021

Yuan Yuan, Zhu Zheng, Lan Ying, Duan Saili, Zhu Ziqing, Zhang Xi, Li Guoyin, Qu Hui, Feng Yanhui, Cai Hui, Song Zewen

Abstract excerpt

Aim: Immunotherapy shows efficacy in only a subset of melanoma patients. Here, we intended to construct a risk score model to predict melanoma patients' sensitivity to immunotherapy. Methods: Integration analyses were performed on melanoma patients from high-dimensional public datasets. The CD8+ T cell infiltration related genes (TIRGs) were selected via TIMER and CIBERSORT algorithm. LASSO Cox regression was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34040608
DOI: 10.3389/fimmu.2021.659444
PMCID: PMC8141567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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