Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The important role of MDM2, RPL5, and TP53 in mycophenolic acid-induced cleft lip and palate.

Medicine - 28 May 2021

Lin Yangyang, Song Tao, Ronde Elsa M, Ma Gang, Cui Huiqin, Xu Meng

Abstract excerpt

ABSTRACT: Mycophenolate embryopathy (MPE) is a mycophenolic acid (MPA)-induced congenital malformation with distinctive symptoms. Cleft lip/palate (CLP) is one of the most common symptoms of MPE. The aim of this study was to screen and verify hub genes involved in MPA-induced CLP and to explore the potential molecular mechanisms underlying MPE.Overlapping genes related to MPA and CLP were obtained from the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cleft Lip
Share to Cleft Palate
Share to Datasets as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mycophenolic Acid

Share to Protein Interaction Mapping

Share to Protein Interaction Maps

Share to Proto-Oncogene Proteins c-mdm2

Share to Ribosomal Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 34032749
DOI: 10.1097/MD.0000000000026101
PMCID: PMC8154508

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The important role of MDM2, RPL5, and TP53 in mycophenolic acid-induced cleft lip and palate.PMID 34032749Read ↗

Cleft Palate Induced by Mycophenolate Mofetil Is Associated with miR-4680-3p and Let-7c-5p in Human Palate CellsSemantic proximity Read ↗

Mycophenolic acid response biomarkers: a cell line model system-based genome-wide screen.Semantic proximity Read ↗

MicroRNA-655-3p and microRNA-497-5p inhibit cell proliferation in cultured human lip cells through the regulation of genes related to human cleft lipSemantic proximity Read ↗

Identification of key gene biomarkers and pathways related to Dent disease in CLCN5 knockout mice by bioinformatics analysisSemantic proximity Read ↗

The essential role of cytoskeleton and ciliary system alterations in the development of congenital pulmonary airway malformationsSemantic proximity Read ↗

Homology Modeling and Virtual Screening of Proteins Related to PXE and PXE-like Diseases: Insights for Overlapping Metabolites.Semantic proximity Read ↗

Functions of MAPR (Membrane-Associated Progesterone Receptor) Family Members As Heme/Steroid-Binding ProteinsSemantic proximity Read ↗

Genetic Background of Medication-Related Osteonecrosis of the Jaw: Current Evidence and Future Perspectives.Semantic proximity Read ↗

Bioinformatic analysis of Msx1 and Msx2 involved in craniofacial development.Semantic proximity Read ↗

PharmGKB summary: mycophenolic acid pathway.Semantic proximity Read ↗

Idiopathic and Heritable PAH Perturb Common Molecular Pathways, Correlated with Increased MSX1 ExpressionSemantic proximity Read ↗

Pseudoxanthoma elasticum: a clinical, histopathological, and molecular update.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.