Article
Reprogramming oral epithelial keratinocytes into a pluripotent phenotype for tissue regeneration.
Clinical and experimental dental research - 1 Dec 2021
Bazina Fayrouz, Brouxhon Sabine M, Kyrkanides Stephanos
Abstract excerpt
OBJECTIVES: We set out to reprogram adult somatic oral epithelial keratinocytes into pluripotent cells for regenerative dentistry. SETTING AND SAMPLE POPULATION: Immortalized murine oral keratinocyte cell (IMOK) line raised from adult mouse mucosa were cultured in vitro in our studies. MATERIALS AND METHODS: Adult murine oral epithelial keratinocytes were chronically treated with TGF-β1 in vitro, and the...
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