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Directed reprogramming of comprehensively characterized dental pulp stem cells extracted from natal tooth

12 Apr 2018

Abstract excerpt

The aim of this study was to extensively characterise natal dental pulp stem cells (nDPSC) and assess their efficiency to generate human induced pluripotent stem cells (hiPSC). A number of distinguishing features prompted us to choose nDPSC over normal adult DPSC, in that they differed in cell surface marker expression and initial doubling time. In addition, nDPSC expressed 17 out of 52 pluripotency genes we...

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PMID: 29670257
DOI: 10.1038/s41598-018-24421-z

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