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Article

Surface attachment, promoted by the actomyosin system of Toxoplasma gondii is important for efficient gliding motility and invasion.

BMC biology - 18 Jan 2017

Whitelaw Jamie A, Latorre-Barragan Fernanda, Gras Simon, Pall Gurman S, Leung Jacqueline M, Heaslip Aoife, Egarter Saskia, Andenmatten Nicole, Nelson Shane R, Warshaw David M, Ward Gary E, Meissner Markus

Abstract excerpt

BACKGROUND: Apicomplexan parasites employ a unique form of movement, termed gliding motility, in order to invade the host cell. This movement depends on the parasite's actomyosin system, which is thought to generate the force during gliding. However, recent evidence questions the exact molecular role of this system, since mutants for core components of the gliding machinery, such as parasite actin or subunits of...

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Identifiers

PMID: 28100223
DOI: 10.1186/s12915-016-0343-5
PMCID: PMC5242020

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