Article
The toxoplasma Acto-MyoA motor complex is important but not essential for gliding motility and host cell invasion.
PloS one - 1 Jan 2014
Egarter Saskia, Andenmatten Nicole, Jackson Allison J, Whitelaw Jamie A, Pall Gurman, Black Jennifer Ann, Ferguson David J P, Tardieux Isabelle, Mogilner Alex, Meissner Markus
Abstract excerpt
Apicomplexan parasites are thought to actively invade the host cell by gliding motility. This movement is powered by the parasite's own actomyosin system, and depends on the regulated polymerisation and depolymerisation of actin to generate the force for gliding and host cell penetration. Recent studies demonstrated that Toxoplasma gondii can invade the host cell in the absence of several core components of the...
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