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Canine induced pluripotent stem cell maintenance under feeder‐free and chemically‐defined conditions

19 May 2021

Abstract excerpt

Canine induced pluripotent stem cells (ciPSCs) provide a platform for regenerative veterinary medicine, disease modeling, and drug discovery. However, in the conventional method, ciPSCs are maintained using chemically-undefined media containing unknown animal components under on-murine embryonic fibroblast feeder conditions, which were reported to modify cell surface of iPSCs and increases the risk of immune...

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PMID: 34010985
DOI: 10.1002/mrd.23478

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