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Macrofollicular variant follicular thyroid tumors are DICER1 mutated and exhibit distinct histological features

18 May 2021

Abstract excerpt

AIMS: DICER1 germline mutations cause DICER1 syndrome, in which multinodular goitre is a common feature. Recently, somatic DICER1 mutations have been reported in sporadic thyroid carcinomas, of which the newly described macrofollicular variant of follicular thyroid carcinoma (MV-FTC) seems particularly enriched for this aberrancy. We report here histological and genetic findings in five follicular thyroid tumours...

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PMID: 34008223
DOI: 10.1111/his.14416

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