Genomic features of rapid versus late relapse in triple negative breast cancer.

doi:10.1186/s12885-021-08320-7

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Genomic features of rapid versus late relapse in triple negative breast cancer.

BMC cancer - 18 May 2021

Zhang Yiqing, Asad Sarah, Weber Zachary, Tallman David, Nock William, Wyse Meghan, Bey Jerome F, Dean Kristin L, Adams Elizabeth J, Stockard Sinclair, Singh Jasneet, Winer Eric P, Lin Nancy U, Jiang Yi-Zhou, Ma Ding, Wang Peng, Shi Leming, Huang Wei, Shao Zhi-Ming, Cherian Mathew, Lustberg Maryam B, Ramaswamy Bhuvaneswari, Sardesai Sagar, VanDeusen Jeffrey, Williams Nicole, Wesolowski Robert, Obeng-Gyasi Samilia, Sizemore Gina M, Sizemore Steven T, Verschraegen Claire, Stover Daniel G

Abstract excerpt

BACKGROUND: Triple-negative breast cancer (TNBC) is a heterogeneous disease and we have previously shown that rapid relapse of TNBC is associated with distinct sociodemographic features. We hypothesized that rapid versus late relapse in TNBC is also defined by distinct clinical and genomic features of primary tumors. METHODS: Using three publicly-available datasets, we identified 453 patients diagnosed with...

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Identifiers

PMID: 34006255
DOI: 10.1186/s12885-021-08320-7
PMCID: PMC8130400

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