Article
Quantum Cascade Laser-Based Infrared Imaging as a Label-Free and Automated Approach to Determine Mutations in Lung Adenocarcinoma.
The American journal of pathology - 1 Jul 2021
Goertzen Nina, Pappesch Roberto, Fassunke Jana, Brüning Thomas, Ko Yon-Dschun, Schmidt Joachim, Großerueschkamp Frederik, Buettner Reinhard, Gerwert Klaus
Abstract excerpt
Therapeutic decisions in lung cancer critically depend on the determination of histologic types and oncogene mutations. Therefore, tumor samples are subjected to standard histologic and immunohistochemical analyses and examined for relevant mutations using comprehensive molecular diagnostics. In this study, an alternative diagnostic approach for automatic and label-free detection of mutations in lung...
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