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Article

CCL21 activation of the MALAT1/SRSF1/mTOR axis underpins the development of gastric carcinoma

17 May 2021

Abstract excerpt

BACKGROUND: As a significant cause of malignancy mortality, gastric carcinoma (GC) has been well documented to be an often-fatal diagnosis. Despite the limitations of effective therapy, immunotherapy has emerged as a promising therapeutic approach capable of killing cancer cells via the immune system. The current study was conducted to investigate the effect of cytokine C-C motif chemokine ligand 21 (CCL21) on GC...

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PMID: 34001131
DOI: 10.1186/s12967-021-02806-5

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