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Article

Tumor subtype defines distinct pathways of molecular and clinical progression in primary prostate cancer

16 May 2021

Abstract excerpt

BACKGROUNDMolecular characterization of prostate cancer (PCa) has revealed distinct subclasses based on underlying genomic alterations occurring early in the natural history of the disease. However, how these early alterations influence subsequent molecular events and the course of the disease over its long natural history remains unclear.METHODSWe explored the molecular and clinical progression of different...

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PMID: 33998599
DOI: 10.1172/jci147878

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