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Regulation of ferroptosis in cancer cells by YAP/TAZ and Hippo pathways: The therapeutic implications

18 May 2020

Abstract excerpt

Ferroptosis is a novel form of iron-dependent cell death characterized by lipid peroxidation. While the importance and disease relevance of ferroptosis is gaining recognition, much remains unknown about various genetic and non-genetic determinants of ferroptosis. Hippo signaling pathway is an evolutionarily conserved pathway that responds to various environmental cues and controls organ size, cell proliferation,...

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PMID: 33997171
DOI: 10.1016/j.gendis.2020.05.004

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