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Article

Histopathological image and gene expression pattern analysis for predicting molecular features and prognosis of head and neck squamous cell carcinoma.

Cancer medicine - 1 Jul 2021

Chen Linyan, Zeng Hao, Zhang Mingxuan, Luo Yuling, Ma Xuelei

Abstract excerpt

BACKGROUND: Histopathological image features offer a quantitative measurement of cellular morphology, and probably help for better diagnosis and prognosis in head and neck squamous cell carcinoma (HNSCC). METHODS: We first used histopathological image features and machine-learning algorithms to predict molecular features of 212 HNSCC patients from The Cancer Genome Atlas (TCGA). Next, we divided TCGA-HNSCC cohort...

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Identifiers

PMID: 33987946
DOI: 10.1002/cam4.3965
PMCID: PMC8267162

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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