Article
Association of NQO1Pro187Ser polymorphism with clinical outcomes and survival of lung cancer patients treated with platinum chemotherapy.
Personalized medicine - 1 Jul 2021
Walia Harleen Kaur, Singh Navneet, Sharma Siddharth
Abstract excerpt
Background: The study was carried out to evaluate the association of NQO1 P187S polymorphism in North Indian lung cancer (LC) patients. We determined the effect of this polymorphic variant on the survival of LC patients. Patients & methods/results: This case-control study comprised a total of 1100 subjects. The genotyping was carried out using PCR-RFLP and statistical analysis was carried out. The variant TT...
Topics
- Case-Control Studies
- Genotype
- Humans
- Lung Neoplasms
- Platinum
- Polymorphism, Genetic