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Article

Gene expression derived from alternative promoters improves prognostic stratification in multiple myeloma

10 May 2021

Abstract excerpt

Clinical and genetic risk factors are currently used in multiple myeloma (MM) to stratify patients and to design specific therapies. However, these systems do not capture the heterogeneity of the disease supporting the development of new prognostic factors. In this study, we identified active promoters and alternative active promoters in 6 different B cell subpopulations, including bone-marrow plasma cells, and...

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PMID: 33972667
DOI: 10.1038/s41375-021-01263-9

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