Article
Genoppi is an open-source software for robust and standardized integration of proteomic and genetic data.
Nature communications - 10 May 2021
Pintacuda Greta, Lassen Frederik H, Hsu Yu-Han H, Kim April, Martín Jacqueline M, Malolepsza Edyta, Lim Justin K, Fornelos Nadine, Eggan Kevin C, Lage Kasper
Abstract excerpt
Combining genetic and cell-type-specific proteomic datasets can generate biological insights and therapeutic hypotheses, but a technical and statistical framework for such analyses is lacking. Here, we present an open-source computational tool called Genoppi (lagelab.org/genoppi) that enables robust, standardized, and intuitive integration of quantitative proteomic results with genetic data. We use Genoppi to...
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