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Article

Cell-free DNA copy number variations predict efficacy of immune checkpoint inhibitor-based therapy in hepatobiliary cancers.

Journal for immunotherapy of cancer - 1 May 2021

Yang Xu, Hu Ying, Yang Keyan, Wang Dongxu, Lin Jianzhen, Long Junyu, Xie Fucun, Mao Jinzhu, Bian Jin, Guan Mei, Pan Jie, Huo Li, Hu Ke, Yang Xiaobo, Mao Yilei, Sang Xinting, Zhang Jiao, Wang Xi, Zhang Henghui, Zhao Haitao

Abstract excerpt

BACKGROUND: This study was designed to screen potential biomarkers in plasma cell-free DNA (cfDNA) for predicting the clinical outcome of immune checkpoint inhibitor (ICI)-based therapy in advanced hepatobiliary cancers. METHODS: Three cohorts including 187 patients with hepatobiliary cancers were recruited from clinical trials at the Peking Union Medical College Hospital. Forty-three patients received...

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Identifiers

PMID: 33972389
DOI: 10.1136/jitc-2020-001942
PMCID: PMC8112417

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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