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Article

The role of caveolin-1 and endothelial nitric oxide synthase polymorphisms in susceptibility to prostate cancer.

International journal of experimental pathology - 1 Dec 2021

Aliyari Mahdieh, Elieh Ali Komi Daniel, Kiani Amir, Moradi Mahmoudreza, Tanhapour Maryam, Rahimi Zohreh, Mozafari Hadi, Mohammadi-Noori Ehsan, Pourmotabbed Tayebeh, Vaisi-Raygani Asad, Bahrehmand Fariborz

Abstract excerpt

Caveolin-1(cav-1) is overexpressed in prostate cancer (PC) and is associated with progression of the disease. We investigated the effects of CAV1-T29107A and endothelial nitric oxide synthase (eNOS) G894T polymorphisms on the serum levels of testosterone, NO and prostate-specific antigen (PSA) in patients with PC. We genotyped cav-1 and eNOS genes in 112 PC patients and 150 healthy controls by PCR-RFLP. Serum...

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Identifiers

PMID: 33964050
DOI: 10.1111/iep.12394
PMCID: PMC8626621

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