Article
Effect of early-life antibiotic exposure and IL-13 polymorphism on atopic dermatitis phenotype.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Oct 2021
Park Min Jee, Lee So-Yeon, Lee Si Hyeon, Kang Mi-Jin, Song Kun Baek, Jung Sungsu, Yoon Ji-Sun, Suh Dong In, Shin Youn Ho, Kim Kyung Won, Ahn Kangmo, Hong Soo-Jong
Abstract excerpt
BACKGROUND: Although atopic dermatitis (AD) is associated with certain gene variants, the rapidly increasing incidence of AD suggests that environmental factors contribute to disease development. In this study, we investigated the association of AD incidence and phenotype with antibiotic exposure within 6 months of age, considering the dose administered and genetic risk. METHODS: This study included 1637 children...
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