Additive effect between IL-13 polymorphism and cesarean section delivery/prenatal antibiotics use on atopic dermatitis: a birth cohort study (COCOA).

doi:10.1371/journal.pone.0096603

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Article

Additive effect between IL-13 polymorphism and cesarean section delivery/prenatal antibiotics use on atopic dermatitis: a birth cohort study (COCOA).

PloS one - 1 Jan 2014

Lee So-Yeon, Yu Jinho, Ahn Kang-Mo, Kim Kyung Won, Shin Youn Ho, Lee Kyung-Shin, Hong Seo Ah, Jung Young-Ho, Lee Eun, Yang Song-I, Seo Ju-Hee, Kwon Ji-Won, Kim Byoung-Ju, Kim Hyo-Bin, Kim Woo-Kyung, Song Dae Jin, Jang Gwang Cheon, Shim Jung Yeon, Lee Soo-Young, Kwon Ja-Young, Choi Suk-Joo, Lee Kyung-Ju, Park Hee Jin, Won Hye-Sung, Yoo Ho-Sung, Kang Mi-Jin, Kim Hyung-Young, Hong Soo-Jong

Abstract excerpt

BACKGROUND: Although cesarean delivery and prenatal exposure to antibiotics are likely to affect the gut microbiome in infancy, their effect on the development of atopic dermatitis (AD) in infancy is unclear. The influence of individual genotypes on these relationships is also unclear. To evaluate with a prospective birth cohort study whether cesarean section, prenatal exposure to antibiotics, and susceptible...

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PMID: 24848505
DOI: 10.1371/journal.pone.0096603
PMCID: PMC4029558

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