Article
Ovine β-globin gene: A new qPCR for rapid haplotype identification and association with susceptibility to Haemonchus contortus infection.
Veterinary parasitology - 1 Jun 2021
Okino Cintia Hiromi, Méo Niciura Simone Cristina, Barbosa Toscano João Henrique, Esteves Sérgio Novita, Dos Santos Isabella Barbosa, von Haehling Marei Borsch, Figueiredo Amanda, de Sena Oliveira Márcia Cristina, Chagas Ana Carolina de Souza
Abstract excerpt
Two β-globin allelic haplotypes (A and B) were identified in domestic sheep, wherein animals which are homozygous for βB allele (BB haplotype) have a deletion of pre-adult βC-globin and consequently are less tolerant to anemia and hypoxia. Since Haemonchus contortus infection, is associated with severe anemia, studies performed from 1960s to 1990s investigated the association between β-globin haplotype and...
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