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Article

Downregulation of miR‐497‐5p Improves Sepsis‐Induced Acute Lung Injury by Targeting IL2RB

1 Jan 2021

Abstract excerpt

Introduction. Acute lung injury (ALI) induced by sepsis is a process related to inflammatory reactions, which involves lung cell apoptosis and production of inflammatory cytokine. Here, lipopolysaccharide (LPS) was applied to stimulate the mouse or human normal lung epithelial cell line (BEAS‐2B) to construct a sepsis model in vivo and in vitro, and we also investigated the effect of miR‐497‐5p on sepsis‐induced...

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PMID: 33954185
DOI: 10.1155/2021/6624702

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