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Article

Epigenomes in Cardiovascular Disease.

Circulation research - 25 May 2018

Rosa-Garrido Manuel, Chapski Douglas J, Vondriska Thomas M

Abstract excerpt

If unifying principles could be revealed for how the same genome encodes different eukaryotic cells and for how genetic variability and environmental input are integrated to impact cardiovascular health, grand challenges in basic cell biology and translational medicine may succumb to experimental dissection. A rich body of work in model systems has implicated chromatin-modifying enzymes, DNA methylation,...

Topics

Cardiovascular Diseases
Cardiovascular Physiological Phenomena
Cell Survival
Chromatin
Chromatin Assembly and Disassembly
DNA Methylation
Epigenesis, Genetic
Epigenomics
Gene-Environment Interaction
Genetic Predisposition to Disease
Histone Deacetylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Histones

Humans

Nucleosomes

RNA, Untranslated

Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 29798902
DOI: 10.1161/CIRCRESAHA.118.311597
PMCID: PMC5976233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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