Article
Evidence-Based Assessment of Genes in Dilated Cardiomyopathy.
Circulation - 6 Jul 2021
Jordan Elizabeth, Peterson Laiken, Ai Tomohiko, Asatryan Babken, Bronicki Lucas, Brown Emily, Celeghin Rudy, Edwards Matthew, Fan Judy, Ingles Jodie, James Cynthia A, Jarinova Olga, Johnson Renee, Judge Daniel P, Lahrouchi Najim, Lekanne Deprez Ronald H, Lumbers R Thomas, Mazzarotto Francesco, Medeiros Domingo Argelia, Miller Rebecca L, Morales Ana, Murray Brittney, Peters Stacey, Pilichou Kalliopi, Protonotarios Alexandros, Semsarian Christopher, Shah Palak, Syrris Petros, Thaxton Courtney, van Tintelen J Peter, Walsh Roddy, Wang Jessica, Ware James, Hershberger Ray E
Abstract excerpt
BACKGROUND: Each of the cardiomyopathies, classically categorized as hypertrophic cardiomyopathy, dilated cardiomyopathy (DCM), and arrhythmogenic right ventricular cardiomyopathy, has a signature genetic theme. Hypertrophic cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy are largely understood as genetic diseases of sarcomere or desmosome proteins, respectively. In contrast, >250 genes...
Topics
- Cardiomyopathy, Dilated
- Evidence-Based Medicine
- Expert Testimony
- Genetic Predisposition to Disease
- Genetic Testing
- Humans