Article
Using whole genome sequence findings to assess gene-disease causality in cardiomyopathy and arrhythmia patients.
Future cardiology - 1 Sept 2023
Krishnan Aishwarya Rajesh, Schwartz Marci Lb, Somerville Cherith, Ding Qiliang, Kim Raymond H
Abstract excerpt
Aim: The genetic etiologies of cardiomyopathies and arrhythmias have not been fully elucidated. Materials & methods: Research findings from genome analyses in a cardiomyopathy and arrhythmia cohort were gathered. Gene-disease relationships from two databases were compared with patient phenotypes. A literature review was conducted for genes with limited evidence. Results: Of 43 genes with candidate findings from...
Topics
- Humans
- Cardiomyopathies
- Arrhythmias, Cardiac
- Phenotype