Genetic and environmental influences on odor identification ability in the very old.

doi:10.1037/a0023263

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Article

Genetic and environmental influences on odor identification ability in the very old.

Psychology and aging - 1 Dec 2011

Doty Richard L, Petersen Inge, Mensah Nii, Christensen Kaare

Abstract excerpt

Odor identification ability and cognition were measured in a population-based cohort of 1,222 very old twins and singletons, including 91 centenarians. Heritability for identifying odors was low, in contrast to that for cognition. Common genes were found to contribute to both olfaction and cognition. In a multiple regression model, sex, age, cognitive function, and smoking, but not APOEε4 status, were significant...

Topics

Age Factors
Aged
Aged, 80 and over
Aging
Apolipoprotein E4
Cognition
Denmark
Discrimination, Psychological
Epidemiologic Methods
Female
Genotype
Humans
Male
Neuropsychological Tests
Odorants

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PMID: 21639645
DOI: 10.1037/a0023263
PMCID: PMC3631779

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Olfaction Disorders

Phenotype

Sex Factors