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Extracellular vesicle-based EGFR genotyping in bronchoalveolar lavage fluid from treatment-naive non-small cell lung cancer patients

1 Dec 2019

Abstract excerpt

BACKGROUND: Extracellular vesicles (EV) have been proven to contain double-stranded DNA reflecting the mutational status of the parental tumor cells in non-small cell lung cancer (NSCLC), which can be translated into clinically useful EV-based liquid biopsy for Epidermal growth factor receptor (EGFR) genotyping using bronchoalveolar lavage fluid (BALF) obtained from tumor site. METHODS: Patients subjected for an...

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Extracellular vesicles in disease
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Lung Cancer Research Studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32010582
DOI: 10.21037/tlcr.2019.12.16

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