Article
Gene mutations in acute promyelocytic leukemia early death in patients treated with arsenic trioxide alone.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Oct 2021
Chen Xiaotong, Fan Shengjin, Zhao Yanqiu, Zhou Jin
Abstract excerpt
PURPOSE: APL patients have recurrent alterations in FLT3, WT1, NRAS and KRAS. Gene mutations have a strong potential for involvement in pathogenesis and may have potential effects on the clinical manifestations. Gene mutations may even be associated with early death (ED) in APL patients. However, there is little published information on mutations in APL patients and whether they are attributed to early death....
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