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Article

Computational principles and challenges in single-cell data integration.

Nature biotechnology - 1 Oct 2021

Argelaguet Ricard, Cuomo Anna S E, Stegle Oliver, Marioni John C

Abstract excerpt

The development of single-cell multimodal assays provides a powerful tool for investigating multiple dimensions of cellular heterogeneity, enabling new insights into development, tissue homeostasis and disease. A key challenge in the analysis of single-cell multimodal data is to devise appropriate strategies for tying together data across different modalities. The term 'data integration' has been used to describe...

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PMID: 33941931
DOI: 10.1038/s41587-021-00895-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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