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A guided-inquiry investigation of genetic variants using Oxford nanopore sequencing for an undergraduate molecular biology laboratory course.

Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology - 1 Jul 2021

Rodriguez Princess D, Mariani Michael, Gay Jamie, Hogan Tyler C, Amiel Eyal, Deming Paula B, Frietze Seth

Abstract excerpt

Next Generation Sequencing (NGS) has become an important tool in the biological sciences and has a growing number of applications across medical fields. Currently, few undergraduate programs provide training in the design and implementation of NGS applications. Here, we describe an inquiry-based laboratory exercise for a college-level molecular biology laboratory course that uses real-time MinION deep sequencing...

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PMID: 33939256
DOI: 10.1002/bmb.21514
PMCID: PMC8356555

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