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Associations of genetic variants of lysophosphatidylcholine metabolic enzymes with levels of serum lipids.

Pediatric research - 1 May 2022

Wang Hui, Wang Yang, Song Jie-Yun, Zhang Ping-Ping, Song Qi-Ying, Li Chen-Xiong, Li Li, Wang Hai-Jun

Abstract excerpt

OBJECTIVE: Metabolic disturbance of lysophosphatidylcholine (LPC) is related with dyslipidemia. Therefore, eight single-nucleotide polymorphisms (SNPs) were selected from LPC metabolic enzymes to study their associations with obesity and serum levels of lipids. METHODS: A total of 3305 children were recruited from four independent studies. Eight SNPs of LPC metabolic enzymes were selected and genotyped with the...

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PMID: 33935285
DOI: 10.1038/s41390-021-01549-9

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